
GIST stands for Gastrointestinal Stromal Tumor. It’s a soft tissue sarcoma that can occur anywhere in the digestive tract (GISTs primarily develop in the stomach, accounting for approximately 60% of cases. About 35% occur in the small intestine. Less commonly, GISTs may also originate in the rectum, colon, or esophagus). Very rarely, a GIST can happen in the abdominal cavity—this is called an eGIST.
Gastrointestinal Stromal Tumors (GIST) are quite rare, with an estimated incidence of 10 to 15 cases per million people annually. This translates to approximately 4,500 to 6,700 new cases each year within the European Union. While GIST can occur at any age, it is most commonly diagnosed in individuals in their mid-60s.





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